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Figure 5. Proteomics analysis of iMSC-lEVs. (A) Venn diag r am showing the overlapping and unique proteins in iMSC-lEVs with Vesiclepedia. (B) Gene ontology biological process analysis showed the proteins enriched in iMSC-lEVs. (C) Gene ontology cellular componen t <t>analy</t> sis show ed the pr ot eins enriched in iMSC-lEVs. (D) Gene ont ology molecular function analysis sho w ed the pr oteins enriched in iMSC-lEVs. (E) IPA showed canonical pathway analysis of iMSC-lEVs proteins. (F & G) Western blot analysis showed p-ERK and ERK expression in HMEC-1 cells under different treatments (n = 3/group). iMSC-lEVs: Large extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells; lEVs: Large extracellular vesicles.
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Verlag GmbH proc 20th göttin- gen neurobiol conf
Figure 5. Proteomics analysis of iMSC-lEVs. (A) Venn diag r am showing the overlapping and unique proteins in iMSC-lEVs with Vesiclepedia. (B) Gene ontology biological process analysis showed the proteins enriched in iMSC-lEVs. (C) Gene ontology cellular componen t <t>analy</t> sis show ed the pr ot eins enriched in iMSC-lEVs. (D) Gene ont ology molecular function analysis sho w ed the pr oteins enriched in iMSC-lEVs. (E) IPA showed canonical pathway analysis of iMSC-lEVs proteins. (F & G) Western blot analysis showed p-ERK and ERK expression in HMEC-1 cells under different treatments (n = 3/group). iMSC-lEVs: Large extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells; lEVs: Large extracellular vesicles.
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Figure 5. Proteomics analysis of iMSC-lEVs. (A) Venn diag r am showing the overlapping and unique proteins in iMSC-lEVs with Vesiclepedia. (B) Gene ontology biological process analysis showed the proteins enriched in iMSC-lEVs. (C) Gene ontology cellular componen t <t>analy</t> sis show ed the pr ot eins enriched in iMSC-lEVs. (D) Gene ont ology molecular function analysis sho w ed the pr oteins enriched in iMSC-lEVs. (E) IPA showed canonical pathway analysis of iMSC-lEVs proteins. (F & G) Western blot analysis showed p-ERK and ERK expression in HMEC-1 cells under different treatments (n = 3/group). iMSC-lEVs: Large extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells; lEVs: Large extracellular vesicles.
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RStudio proc package
Figure 5. Proteomics analysis of iMSC-lEVs. (A) Venn diag r am showing the overlapping and unique proteins in iMSC-lEVs with Vesiclepedia. (B) Gene ontology biological process analysis showed the proteins enriched in iMSC-lEVs. (C) Gene ontology cellular componen t <t>analy</t> sis show ed the pr ot eins enriched in iMSC-lEVs. (D) Gene ont ology molecular function analysis sho w ed the pr oteins enriched in iMSC-lEVs. (E) IPA showed canonical pathway analysis of iMSC-lEVs proteins. (F & G) Western blot analysis showed p-ERK and ERK expression in HMEC-1 cells under different treatments (n = 3/group). iMSC-lEVs: Large extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells; lEVs: Large extracellular vesicles.
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Figure 5. Proteomics analysis of iMSC-lEVs. (A) Venn diag r am showing the overlapping and unique proteins in iMSC-lEVs with Vesiclepedia. (B) Gene ontology biological process analysis showed the proteins enriched in iMSC-lEVs. (C) Gene ontology cellular componen t analy sis show ed the pr ot eins enriched in iMSC-lEVs. (D) Gene ont ology molecular function analysis sho w ed the pr oteins enriched in iMSC-lEVs. (E) IPA showed canonical pathway analysis of iMSC-lEVs proteins. (F & G) Western blot analysis showed p-ERK and ERK expression in HMEC-1 cells under different treatments (n = 3/group). iMSC-lEVs: Large extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells; lEVs: Large extracellular vesicles.

Journal: Nanomedicine (London, England)

Article Title: Large extracellular vesicles from induced pluripotent stem cell-marrow stem cells enhance limb angiogenesis via ERK/MAPK.

doi: 10.1080/17435889.2024.2363743

Figure Lengend Snippet: Figure 5. Proteomics analysis of iMSC-lEVs. (A) Venn diag r am showing the overlapping and unique proteins in iMSC-lEVs with Vesiclepedia. (B) Gene ontology biological process analysis showed the proteins enriched in iMSC-lEVs. (C) Gene ontology cellular componen t analy sis show ed the pr ot eins enriched in iMSC-lEVs. (D) Gene ont ology molecular function analysis sho w ed the pr oteins enriched in iMSC-lEVs. (E) IPA showed canonical pathway analysis of iMSC-lEVs proteins. (F & G) Western blot analysis showed p-ERK and ERK expression in HMEC-1 cells under different treatments (n = 3/group). iMSC-lEVs: Large extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells; lEVs: Large extracellular vesicles.

Article Snippet: Prote omic anal ysis The iMSCs-lEVs prot eomic analy sis proc ess was carried out by the Shanghai Applied Protein Technology Company (Shanghai, China).

Techniques: Western Blot, Expressing, Derivative Assay